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Synthetic protein alignments by CCMgen quantify noise in residue-residue contact prediction
Compensatory mutations between protein residues in physical contact can manifest themselves as statistical couplings between the corresponding columns in a multiple sequence alignment (MSA) of the protein family. Conversely, large coupling coefficients predict residue contacts. Methods for de-novo p...
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| Veröffentlicht in: | PLoS Comput Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237422/ https://ncbi.nlm.nih.gov/pubmed/30395601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006526 |
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