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Serum sphingolipid levels associate with upcoming virologic events and HBV genotype D in a cohort of patients with HBeAg-negative HBV infection

OBJECTIVES: Sphingolipids (SLs) have been implicated as potent regulators of the hepatitis B virus (HBV) life cycle. We investigated the SL biomarker potential regarding virologic endpoints in a prospective subgroup of patients with HBeAg-negative chronic HBV infection. METHODS: From 2009–2016 98 pa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mücke, Victoria Therese, Jakobi, Katja, Knop, Viola, Thomas, Dominique, Mücke, Marcus Maximilian, Peiffer, Kai-Henrik, Zeuzem, Stefan, Sarrazin, Christoph, Pfeilschifter, Josef, Grammatikos, Georgios
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237377/
https://ncbi.nlm.nih.gov/pubmed/30439997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207293
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