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GENE-ENVIRONMENT INTERACTIONS IN CASE-CONTROL STUDIES WITH SILENT DISEASE

Genome-Wide Association Studies (GWAS) often measure Gene-Environment (GxE) interactions. We consider the problem of accurately estimating a GxE interaction in a case/control GWAS when a subset of the controls have silent, or undiagnosed, disease and the frequency of the silent disease varies by the...

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Vydáno v:Genet Epidemiol
Hlavní autoři: Lobach, Iryna, Sampson, Joshua, Lobach, Siarhei, Zhang, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237277/
https://ncbi.nlm.nih.gov/pubmed/29896809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22135
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