Glucagon-like peptide-1 and its analogues act in the dorsal raphe and modulate central serotonin to reduce appetite and body weight

Glucagon-like peptide-1 (GLP-1) and serotonin play critical roles in energy balance regulation. Both systems are exploited clinically as anti-obesity strategies. Surprisingly whether they interact in order to regulate energy balance is poorly understood. Here we investigated mechanisms by which GLP-...

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Veröffentlicht in:Diabetes
Hauptverfasser: Anderberg, Rozita H, Richard, Jennifer E, Eerola, Kim, Lopez-Ferreras, Lorena, Banke, Elin, Hansson, Caroline, Nissbrandt, Hans, Berqquist, Filip, Gribble, Fiona M, Reimann, Frank, Wernstedt Asterholm, Ingrid, Lamy, Christophe M, Skibicka, Karolina P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237271/
https://ncbi.nlm.nih.gov/pubmed/28057699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0755
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