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Imbalance of immunological synapse-kinapse states reflects tumor escape to immunity in glioblastoma

Since the proper activation of T cells requires the physical interaction with target cells through the formation of immunological synapses (IS), an alteration at this level could be a reason why tumors escape the immune response. As part of their life cycle, it is thought that T cells alternate betw...

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Publicado en:JCI Insight
Autores principales: Díaz, Laura R., Saavedra-López, Elena, Romarate, Leire, Mitxitorena, Izaskun, Casanova, Paola V., Cribaro, George P., Gallego, José M., Pérez-Vallés, Ana, Forteza-Vila, Jerónimo, Alfaro-Cervello, Clara, García-Verdugo, José M., Barcia, Carlos
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237222/
https://ncbi.nlm.nih.gov/pubmed/30232280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120757
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