IL-33 modulates inflammatory brain injury but exacerbates systemic immunosuppression following ischemic stroke

Stroke triggers a complex inflammatory process in which the balance between pro- and antiinflammatory mediators is critical for the development of the brain infarct. However, systemic changes may also occur in parallel with brain inflammation. Here we demonstrate that administration of recombinant I...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Zhang, Shenpeng R., Piepke, Marius, Chu, Hannah X., Broughton, Brad R.S., Shim, Raymond, Wong, Connie H.Y., Lee, Seyoung, Evans, Megan A., Vinh, Antony, Sakkal, Samy, Arumugam, Thiruma V., Magnus, Tim, Huber, Samuel, Gelderblom, Mathias, Drummond, Grant R., Sobey, Christopher G., Kim, Hyun Ah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237219/
https://ncbi.nlm.nih.gov/pubmed/30232272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121560
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