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CTL019 (tisagenlecleucel): CAR-T therapy for relapsed and refractory B-cell acute lymphoblastic leukemia

Over the past decades, survival of patients with acute lymphoblastic leukemia (ALL) has dramatically improved, but the subgroup of patients with relapsed/refractory ALL still continues to have dismal prognosis. As an emerging therapeutic approach, chimeric antigen receptor-modified T-cells (CAR-T) r...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Vairy, Stephanie, Garcia, Julia Lopes, Teira, Pierre, Bittencourt, Henrique
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237143/
https://ncbi.nlm.nih.gov/pubmed/30518999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S138765
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