A carregar...

Efficacy and safety of low-dose Sirolimus in Lymphangioleiomyomatosis

BACKGROUND: Lymphangioleiomyomatosis is a rare disease caused by unregulated activation of mammalian target of rapamycin (mTOR) signalling pathway. Sirolimus showed efficacy in a phase 3 trial of patients with lymphangioleiomyomatosis, but the optimal dose remains unclear. METHODS: We investigated t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Orphanet J Rare Dis
Main Authors: Yoon, Hee-Young, Hwang, Jung Jin, Kim, Dong Soon, Song, Jin Woo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236936/
https://ncbi.nlm.nih.gov/pubmed/30428897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-018-0946-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!