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Immune Surveillance by Natural IgM Is Required for Early Neoantigen Recognition and Initiation of Adaptive Immunity

Early recognition of neoantigen-expressing cells is complex, involving multiple immune cell types. In this study, in vivo, we examined how antigen-presenting cell subtypes coordinate and induce an immunological response against neoantigen-expressing cells, particularly in the absence of a pathogen-a...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Atif, Shaikh M., Gibbings, Sophie L., Redente, Elizabeth F., Camp, Faye A., Torres, Raul M., Kedl, Ross M., Henson, Peter M., Jakubzick, Claudia V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236687/
https://ncbi.nlm.nih.gov/pubmed/29953261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0159OC
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