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Proanthocyanidins exert a neuroprotective effect via ROS/JNK signaling in MPTP-induced Parkinson's disease models in vitro and in vivo

The pathological alterations of Parkinson's disease (PD) predominantly manifest as a loss of dopaminergic neurons in the substantia nigra, which may be caused by oxidative stress damage. Proanthocyanidins (PCs) are a class of compounds found in various plants, which have significant antioxidant...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Chen, Hucheng, Xu, Jiyu, Lv, Yuan, He, Ping, Liu, Chunyan, Jiao, Jie, Li, Shiwei, Mao, Xuhua, Xue, Xue
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236276/
https://ncbi.nlm.nih.gov/pubmed/30272275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9509
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