In vivo evidence for reduced ion channel expression in motor axons of patients with amyotrophic lateral sclerosis

KEY POINTS: The progressive loss of motor units in amyotrophic lateral sclerosis (ALS) is initially compensated for by the reinnervation of denervated muscle fibres by surviving motor axons. A disruption in protein homeostasis is thought to play a critical role in the pathogenesis of ALS. The change...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Howells, James, Matamala, José Manuel, Park, Susanna B., Garg, Nidhi, Vucic, Steve, Bostock, Hugh, Burke, David, Kiernan, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235931/
https://ncbi.nlm.nih.gov/pubmed/30175403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276624
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados