Fecal chromogranins and secretogranins are linked to the fecal and mucosal intestinal bacterial composition of IBS patients and healthy subjects

Altered fecal levels of chromogranins (Cg) and secretogranins (Sg) are demonstrated in irritable bowel syndrome (IBS), but their role in IBS pathophysiology remains unknown. This study aimed to determine if granins are associated with bacterial composition, immune activation and IBS symptoms. Protei...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Sundin, Johanna, Stridsberg, Mats, Tap, Julien, Derrien, Muriel, Le Nevé, Boris, Doré, Joël, Törnblom, Hans, Simrén, Magnus, Öhman, Lena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235916/
https://ncbi.nlm.nih.gov/pubmed/30429499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35241-6
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