IFNL4-ΔG is associated with prostate cancer among men at increased risk of sexually transmitted infections

Sexually transmitted infections can reach the prostate gland where their harmful effects are mediated by innate immunity, including interferons. Humans are polymorphic for the germline dinucleotide variant, rs368234815-TT/ΔG, in the IFNL4 gene encoding interferon λ4. Since the IFNL4-ΔG allele has be...

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Publicado no:Commun Biol
Main Authors: Minas, Tsion Zewdu, Tang, Wei, Smith, Cheryl J., Onabajo, Olusegun O., Obajemu, Adeola, Dorsey, Tiffany H., Jordan, Symone V., Obadi, Obadi M., Ryan, Bríd M., Prokunina-Olsson, Ludmila, Loffredo, Christopher A., Ambs, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235841/
https://ncbi.nlm.nih.gov/pubmed/30456312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0193-5
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