Efficient Purification and LC-MS/MS-based Assay Development for Ten-Eleven Translocation-2 5-Methylcytosine Dioxygenase

The epigenetic transcription regulation mediated by 5-methylcytosine (5mC) has played a critical role in eukaryotic development. Demethylation of these epigenetic marks is accomplished by sequential oxidation by ten-eleven translocation dioxygenases (TET1-3), followed by the thymine-DNA glycosylase-...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Vis Exp
Hlavní autoři: Bhattacharya, Chayan, Dey, Aninda Sundar, Ayon, Navid J., Gutheil, William G., Mukherji, Mridul
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2018
Témata:
This Month in JoVE
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235521/
https://ncbi.nlm.nih.gov/pubmed/30371677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57798
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky