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Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities

Peptides with a high number of cysteines are usually influenced regarding the three-dimensional structure by their disulfide connectivity. It is thus highly important to avoid undesired disulfide bond formation during peptide synthesis, because it may result in a completely different peptide structu...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Heimer, Pascal, Schmitz, Thomas, Bäuml, Charlotte A., Imhof, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235375/
https://ncbi.nlm.nih.gov/pubmed/30346393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58368
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