Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease

Gut homing of immune cells is important for the pathogenesis of inflammatory bowel diseases (IBD). Integrin-dependent cell adhesion to addressins is a crucial step in this process and therapeutic strategies interfering with adhesion have been successfully established. The anti-α4β7 integrin antibody...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Becker, Emily, Schramm, Sebastian, Binder, Marie-Theres, Allner, Clarissa, Wiendl, Maximilian, Neufert, Clemens, Atreya, Imke, Neurath, Markus, Zundler, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2018
Fag:
Immunology and Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235239/
https://ncbi.nlm.nih.gov/pubmed/30295649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58210
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