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Permethrin, a pyrethroid insecticide, regulates ERK1/2 activation through membrane depolarization-mediated pathway in HepG2 hepatocytes

Permethrin is a pyrethroid insecticide that acts thru membrane depolarization and is known to disrupt calcium levels in neurons. Disrupted calcium homeostasis is linked to oxidative stress as well as many other cellular mis-functions and permethrin has been reported to disrupt lipid and glucose meta...

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Publicado en:Food Chem Toxicol
Main Authors: Yang, Jason S., Symington, Steven, Clark, John M., Park, Yeonhwa
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235143/
https://ncbi.nlm.nih.gov/pubmed/30205134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2018.09.009
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