Correlative Light Electron Microscopy (CLEM) for Tracking and Imaging Viral Protein Associated Structures in Cryo-immobilized Cells

Due to its high resolution, electron microscopy (EM) is an indispensable tool for virologists. However, one of the main difficulties when analyzing virus-infected or transfected cells via EM are the low efficiencies of infection or transfection, hindering the examination of these cells. In order to...

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Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Santarella-Mellwig, Rachel, Haselmann, Uta, Schieber, Nicole L., Walther, Paul, Schwab, Yannick, Antony, Claude, Bartenschlager, Ralf, Romero-Brey, Inés
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2018
Soggetti:
This Month in JoVE
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235138/
https://ncbi.nlm.nih.gov/pubmed/30247481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58154
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