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Gene expression of hENT1, dCK, CDA, dCMPD and topoisomerase IIα as an indicator of chemotherapy response in AML treated with cytarabine and daunorubicin

PURPOSE: Acute myeloid leukemia patients are commonly treated with cytarabine (Ara-C) and anthracyclines but the sustained remission rate is not very promising. We explored the role of drug-metabolizing enzymes and transporters in the therapeutic response. PATIENTS AND METHODS: Bone marrow and perip...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Kulsoom, Bibi, Shamsi, Tahir Sultan, Afsar, Nasir Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235003/
https://ncbi.nlm.nih.gov/pubmed/30519105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S181299
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