Generation of Progesterone-Responsive Endometrial Stromal Fibroblasts from Human Induced Pluripotent Stem Cells: Role of the WNT/CTNNB1 Pathway

Defective endometrial stromal fibroblasts (EMSFs) contribute to uterine factor infertility, endometriosis, and endometrial cancer. Induced pluripotent stem cells (iPSCs) derived from skin or bone marrow biopsies provide a patient-specific source that can be differentiated to various cells types. Rep...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Miyazaki, Kaoru, Dyson, Matthew T., Coon V, John S., Furukawa, Yuichi, Yilmaz, Bahar D., Maruyama, Tetsuo, Bulun, Serdar E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234962/
https://ncbi.nlm.nih.gov/pubmed/30392973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.10.002
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