Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

Background: Mutations of the common cytokine receptor gamma chain (γc) cause Severe Combined Immunodeficiency characterized by absent T and NK cell development. Although stem cell therapy restores these lineages, residual immune defects are observed that may result from selective persistence of γc-d...

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Bibliografiske detaljer
Udgivet i:Wellcome Open Res
Main Authors: Beilin, Chiara, Choudhuri, Kaushik, Bouma, Gerben, Malinova, Dessislava, Llodra, Jaime, Stokes, David L., Shimaoka, Motumu, Springer, Timothy A., Dustin, Michael L., Thrasher, Adrian J., Burns, Siobhan O.
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Limited 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234741/
https://ncbi.nlm.nih.gov/pubmed/30483599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14493.2
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