Empagliflozin Increases Cardiac Energy Production in Diabetes: Novel Translational Insights Into the Heart Failure Benefits of SGLT2 Inhibitors

SGLT2 inhibitors have profound benefits on reducing heart failure and cardiovascular mortality in individuals with type 2 diabetes, although the mechanism(s) of this benefit remain poorly understood. Because changes in cardiac bioenergetics play a critical role in the pathophysiology of heart failur...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Verma, Subodh, Rawat, Sonia, Ho, Kim L., Wagg, Cory S., Zhang, Liyan, Teoh, Hwee, Dyck, John E., Uddin, Golam M., Oudit, Gavin Y., Mayoux, Eric, Lehrke, Michael, Marx, Nikolaus, Lopaschuk, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
LEADING EDGE IN TRANSLATIONAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234616/
https://ncbi.nlm.nih.gov/pubmed/30456329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.07.006
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