Whole genome sequencing of Trypanosoma cruzi field isolates reveals extensive genomic variability and complex aneuploidy patterns within TcII DTU

BACKGROUND: Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided into six discrete typing units (DTUs), named TcI-TcVI. TcII is among the major DTUs enrolled in human infections in South America southern cone, where it is associated with severe cardiac and digestive symptom...

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Publicado en:BMC Genomics
Autores principales: Reis-Cunha, João Luís, Baptista, Rodrigo P., Rodrigues-Luiz, Gabriela F., Coqueiro-dos-Santos, Anderson, Valdivia, Hugo O., de Almeida, Laila Viana, Cardoso, Mariana Santos, D’Ávila, Daniella Alchaar, Dias, Fernando Hugo Cunha, Fujiwara, Ricardo Toshio, Galvão, Lúcia M. C., Chiari, Egler, Cerqueira, Gustavo Coutinho, Bartholomeu, Daniella C.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234542/
https://ncbi.nlm.nih.gov/pubmed/30424726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5198-4
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