Impact of somatic and germline mutations on the outcome of systemic mastocytosis

Systemic mastocytosis (SM) is a highly heterogeneous disease with indolent and aggressive forms, with the mechanisms leading to malignant transformation still remaining to be elucidated. Here, we investigated the presence and frequency of genetic variants in 34 SM patients with multilineal KIT D816V...

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Foilsithe in:Blood Adv
Main Authors: Muñoz-González, Javier I., Jara-Acevedo, María, Alvarez-Twose, Iván, Merker, Jason D., Teodosio, Cristina, Hou, Yanli, Henriques, Ana, Roskin, Krishna M., Sanchez-Muñoz, Laura, Tsai, Albert G., Caldas, Carolina, Matito, Almudena, Sánchez-Gallego, J. Ignacio, Mayado, Andrea, Dasilva-Freire, Noelia, Gotlib, Jason R., Escribano, Luis, Orfao, Alberto, García-Montero, Andrés C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2018
Ábhair:
Myeloid Neoplasia
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234367/
https://ncbi.nlm.nih.gov/pubmed/30373888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018020628
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