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A comparative study of non-native N-acyl L-homoserine lactone analogs in two Pseudomonas aeruginosa quorum sensing receptors that share a common native ligand yet inversely regulate virulence

Certain bacteria can coordinate group behaviors via a chemical communication system known as quorum sensing (QS). Gram-negative bacteria typically use N-acyl L-homoserine lactone (AHL) signals and their cognate intracellular LuxR-type receptors for QS. The opportunistic pathogen Pseudomonas aerugino...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Boursier, Michelle E., Manson, Daniel E., Combs, Joshua B., Blackwell, Helen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234094/
https://ncbi.nlm.nih.gov/pubmed/29793752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.05.018
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