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Determination of major histocompatibility class I and class II genetic composition of the Caribbean Primate Center specific pathogen-free rhesus macaque (Macaca mulatta) colony based on massively parallel sequencing

BACKGROUND: Knowledge of MHC composition and distribution in rhesus macaque colonies is critical for management strategies that maximize the utility of this model for biomedical research. METHODS: Variation within the Mamu-A and Mamu-B (class I) and DRB, DQA/B and DPA/B (class II) regions of 379 ani...

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Detalhes bibliográficos
Publicado no:J Med Primatol
Main Authors: KANTHASWAMY, SREETHARAN, OLDT, ROBERT F., NG, JILLIAN, SMITH, DAVID GLENN, MARTÍNEZ, MELWEEN I., SARIOL, CARLOS A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234078/
https://ncbi.nlm.nih.gov/pubmed/29971797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jmp.12353
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