Effect of Serial Infusions of CER-001, a Pre-β High-Density Lipoprotein Mimetic, on Coronary Atherosclerosis in Patients Following Acute Coronary Syndromes in the CER-001 Atherosclerosis Regression Acute Coronary Syndrome Trial: A Randomized Clinical Trial

IMPORTANCE: CER-001 is a negatively charged, engineered pre-β high-density lipoprotein (HDL) mimetic containing apolipoprotein A-I and sphingomyelin. Preliminary studies demonstrated favorable effects of CER-001 on cholesterol efflux and vascular inflammation. A post hoc reanalysis of a previously c...

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Bibliographic Details
Published in:JAMA Cardiol
Main Authors: Nicholls, Stephen J., Andrews, Jordan, Kastelein, John J. P., Merkely, Bela, Nissen, Steven E., Ray, Kausik K., Schwartz, Gregory G., Worthley, Stephen G., Keyserling, Connie, Dasseux, Jean-Louis, Griffith, Liddy, Kim, Susan W., Janssan, Alex, Di Giovanni, Giuseppe, Pisaniello, Anthony D., Scherer, Daniel J., Psaltis, Peter J., Butters, Julie
Format: Artigo
Language:Inglês
Published: American Medical Association 2018
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233644/
https://ncbi.nlm.nih.gov/pubmed/30046828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2018.2121
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