Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction

Acute cardiac rupture and adverse left ventricular (LV) remodeling causing heart failure are serious complications of acute myocardial infarction (MI). While cardio-hepatic interactions have been recognized, their role in MI remains unknown. We treated cultured cardiomyocytes with conditioned media...

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Published in:Sci Rep
Main Authors: Hakuno, Daihiko, Kimura, Masahiro, Ito, Shinji, Satoh, Junko, Nakashima, Yasuhiro, Horie, Takahiro, Kuwabara, Yasuhide, Nishiga, Masataka, Ide, Yuya, Baba, Osamu, Nishi, Hitoo, Nakao, Tetsushi, Nishino, Tomohiro, Nakazeki, Fumiko, Koyama, Satoshi, Hanada, Ritsuko, Randolph, Ruiz R., Endo, Jin, Kimura, Takeshi, Ono, Koh
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233179/
https://ncbi.nlm.nih.gov/pubmed/30425314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35194-w
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