Chargement en cours...

Cholesterol depletion enhances TGF-β Smad signaling by increasing c-Jun expression through a PKR-dependent mechanism

Transforming growth factor-β (TGF-β) plays critical roles in numerous physiological and pathological responses. Cholesterol, a major plasma membrane component, can have pronounced effects on signaling responses. Cells continually monitor cholesterol content and activate multilayered transcriptional...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Shapira, Keren E., Ehrlich, Marcelo, Henis, Yoav I.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233055/
https://ncbi.nlm.nih.gov/pubmed/30091670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-03-0175
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!