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A Review of the Potential Mechanisms of Action of Baclofen in Alcohol Use Disorder

Baclofen, a GABA-B receptor agonist, is a promising treatment for alcohol use disorder (AUD). Its mechanism of action in this condition is unknown. GABA-B receptors interact with many biological systems potentially involved in AUD, including transduction pathways and neurotransmitter systems. Precli...

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Publicat a:Front Psychiatry
Autor principal: de Beaurepaire, Renaud
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232933/
https://ncbi.nlm.nih.gov/pubmed/30459646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2018.00506
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