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Astilbin Inhibits High Glucose-Induced Inflammation and Extracellular Matrix Accumulation by Suppressing the TLR4/MyD88/NF-κB Pathway in Rat Glomerular Mesangial Cells

Diabetic nephropathy (DN) is characterized by inflammatory responses and extracellular matrix (ECM) accumulation. Astilbin is an active natural compound and possesses anti-inflammatory activity. The aim of this study was to evaluate the anti-inflammatory effect of astilbin on high glucose (HG)-induc...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chen, Fang, Zhu, Xiaoguang, Sun, Zhiqiang, Ma, Yali
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232904/
https://ncbi.nlm.nih.gov/pubmed/30459606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01187
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