Zebrafish Larvae Are a Suitable Model to Investigate the Metabolic Phenotype of Drug-Induced Renal Tubular Injury

Prevention and treatment of drug-induced renal injury (DIRI) rely on the availability of sensitive and specific biomarkers of early kidney injury and predictive animal models of human pathophysiology. This study aimed to evaluate the potential of zebrafish larvae as translational model in metabolic...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Morello, Judit, Derks, Rico J. E., Lopes, Susana S., Steenvoorden, Evelyne, Monteiro, Emilia C., Mayboroda, Oleg A., Pereira, Sofia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232664/
https://ncbi.nlm.nih.gov/pubmed/30459607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01193
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