Modulation of Vaccine-Induced CD4 T Cell Functional Profiles by Changes in Components of HIV Vaccine Regimens in Humans

To date, six vaccine strategies have been evaluated in clinical trials for their efficacy at inducing protective immune responses against HIV infection. However, only the ALVAC-HIV/AIDSVAX B/E vaccine (RV144 trial) has demonstrated protection, albeit modestly (31%; P = 0.03). One potential correlate...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pissani, Franco, Schulte, Bianca, Eller, Michael A., Schultz, Bruce T., Ratto-Kim, Silvia, Marovich, Mary, Thongcharoen, Prasert, Sriplienchan, Somchai, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Esser, Stefan, Alter, Galit, Robb, Merlin L., Kim, Jerome H., Michael, Nelson L., Streeck, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232489/
https://ncbi.nlm.nih.gov/pubmed/30209165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01143-18
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