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Sindbis Virus Infection Causes Cell Death by nsP2-Induced Transcriptional Shutoff or by nsP3-Dependent Translational Shutoff

Sindbis virus (SINV) is a representative member of the Alphavirus genus in the Togaviridae family. The hallmark of SINV replication in vertebrate cells is a rapid development of the cytopathic effect (CPE), which usually occurs within 24 h postinfection. Mechanistic understanding of CPE might lead t...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Akhrymuk, Ivan, Frolov, Ilya, Frolova, Elena I.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232463/
https://ncbi.nlm.nih.gov/pubmed/30232189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01388-18
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