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Elevated Glutamate and Glutamine Levels in the Cerebrospinal Fluid of Patients With Probable Alzheimer's Disease and Depression

Recent evidence suggests that Alzheimer's disease (AD) and depression share common mechanisms of pathogenesis. In particular, deregulation of glutamate-mediated excitatory signaling may play a role in brain dysfunction in both AD and depression. We have investigated levels of glutamate and its...

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Pubblicato in:Front Psychiatry
Autori principali: Madeira, Caroline, Vargas-Lopes, Charles, Brandão, Carlos Otávio, Reis, Taylor, Laks, Jerson, Panizzutti, Rogerio, Ferreira, Sergio T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232456/
https://ncbi.nlm.nih.gov/pubmed/30459657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2018.00561
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