Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APP(SWE)/PS1(ΔE9) Transgenic Mice Implicate Cathepsin Z in Alzheimer’s Disease

Neuroinflammation, characterized by chronic activation of the myeloid-derived microglia, is a hallmark of Alzheimer’s disease (AD). Systemic inflammation, typically resulting from infection, has been linked to the progression of AD due to exacerbation of the chronic microglial reaction. However, the...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: Thygesen, Camilla, Ilkjær, Laura, Kempf, Stefan J., Hemdrup, Anne Louise, von Linstow, Christian Ulrich, Babcock, Alicia A., Darvesh, Sultan, Larsen, Martin R., Finsen, Bente
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Neuroscience
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232379/
https://ncbi.nlm.nih.gov/pubmed/30459560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00397
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