Exploration of the glutamate-mediated retinal excitotoxic damage: a rat model of retinal neurodegeneration

AIM: To explore the more suitable concentration of glutamate or N-methyl-D-aspartic acid (NMDA) for intravitreal injection to establish a rat model of retinal neurodegeneration. METHODS: We injected different doses of glutamate (20 or 50 nmol) or NMDA (40 nmol) into the vitreous chambers of rats, th...

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Detalhes bibliográficos
Publicado no:Int J Ophthalmol
Main Authors: Gao, Ling, Zheng, Qi-Jun, Ai, Li-Qian-Yu, Chen, Kai-Jian, Zhou, Yuan-Guo, Ye, Jian, Liu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2018
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232320/
https://ncbi.nlm.nih.gov/pubmed/30450303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2018.11.03
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