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LEF-1 is a Sensitive Marker of Cribriform Morular Variant of Papillary Thyroid Carcinoma

Cribriform morular variant of PTC (CMV-PTC) frequently shows activation of the CTNNB1/Wnt pathway with nuclear accumulation of beta catenin. The utility of LEF-1, also in the CTNNB1/WNT pathway, in the diagnosis of CMV-PTC has not been previously studied. LEF-1 immunohistochemistry was performed on...

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Detalhes bibliográficos
Publicado no:Head Neck Pathol
Main Authors: Mohindra, Shalini, Sakr, Hany, Sturgis, Charles, Chute, Deborah J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232206/
https://ncbi.nlm.nih.gov/pubmed/29243023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12105-017-0873-3
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