REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice

In mice, imprinted X chromosome inactivation (iXCI) of the paternal X in the pre-implantation embryo and extraembryonic tissues is followed by X reactivation in the inner cell mass (ICM) of the blastocyst to facilitate initiation of random XCI (rXCI) in all embryonic tissues. RNF12 is an E3 ubiquiti...

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Publié dans:Nat Commun
Auteurs principaux: Gontan, Cristina, Mira-Bontenbal, Hegias, Magaraki, Aristea, Dupont, Catherine, Barakat, Tahsin Stefan, Rentmeester, Eveline, Demmers, Jeroen, Gribnau, Joost
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232137/
https://ncbi.nlm.nih.gov/pubmed/30420655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07060-w
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