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Calcium stabilizes the strongest protein fold

Staphylococcal pathogens adhere to their human targets with exceptional resilience to mechanical stress, some propagating force to the bacterium via small, Ig-like folds called B domains. We examine the mechanical stability of these folds using atomic force microscopy-based single-molecule force spe...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Milles, Lukas F., Unterauer, Eduard M., Nicolaus, Thomas, Gaub, Hermann E.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232131/
https://ncbi.nlm.nih.gov/pubmed/30420680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07145-6
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