SPINK1, PRSS1, CTRC, and CFTR Genotypes Influence Disease Onset and Clinical Outcomes in Chronic Pancreatitis

OBJECTIVES: Rare pathogenic variants in the SPINK1, PRSS1, CTRC, and CFTR genes have been strongly associated with a risk of developing chronic pancreatitis (CP). However, their potential impact on the age of disease onset and clinical outcomes, as well as their potential interactions with environme...

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Published in:Clin Transl Gastroenterol
Main Authors: Zou, Wen-Bin, Tang, Xin-Ying, Zhou, Dai-Zhan, Qian, Yang-Yang, Hu, Liang-Hao, Yu, Fei-Fei, Yu, Dong, Wu, Hao, Deng, Shun-Jiang, Lin, Jin-Huan, Zhao, An-Jing, Zhao, Zhen-Hua, Wu, Hong-Yu, Zhu, Jia-Hui, Qian, Wei, Wang, Lei, Xin, Lei, Wang, Min-Jun, Wang, Li-Juan, Fang, Xue, He, Lin, Masson, Emmanuelle, Cooper, David N., Férec, Claude, Li, Zhao-Shen, Chen, Jian-Min, Liao, Zhuan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group US 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232107/
https://ncbi.nlm.nih.gov/pubmed/30420730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41424-018-0069-5
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