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Sarcomere-based genetic enhancement of systolic cardiac function in a murine model of dilated cardiomyopathy

Diminished cardiac contractile function is a characteristic feature of dilated cardiomyopathy (DCM) and many other heart failure (HF) causing etiologies. We tested the hypothesis that targeting the sarcomere to increase cardiac contractility can effectively prevent the DCM phenotype in muscle-LIM pr...

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Detalhes bibliográficos
Publicado no:Int J Cardiol
Main Authors: Li, Jiayang, Gresham, Kenneth S., Mamidi, Ranganath, Doh, Chang Yoon, Wan, Xiaoping, Deschenes, Isabelle, Stelzer, Julian E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231975/
https://ncbi.nlm.nih.gov/pubmed/30279005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2018.09.073
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