Improved islet recovery and efficacy through co-culture and co-transplantation of islets with human adipose-derived mesenchymal stem cells

Islet transplantation is an established clinical procedure for select patients with type 1 diabetes and severe hypoglycemia to stabilize glycemic control. Post-transplant, substantial beta cell mass is lost, necessitating multiple donors to maintain euglycemia. A potential strategy to augment islet...

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Опубликовано в: :PLoS One
Главные авторы: Gamble, Anissa, Pawlick, Rena, Pepper, Andrew R., Bruni, Antonio, Adesida, Adetola, Senior, Peter A., Korbutt, Gregory S., Shapiro, A. M. James
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231609/
https://ncbi.nlm.nih.gov/pubmed/30419033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206449
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