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Interaction of Half Oxa-/Half cis-Platin Complex with Human Superoxide Dismutase and Induced Reduction of Neurotoxicity
[Image: see text] The formation of amorphous protein aggregates containing human superoxide dismutase (hSOD1) is thought to be involved in amyotrophic lateral sclerosis onset. cis-Platin inhibits the oligomerization of apo hSOD1, but its toxicity precludes any possible use in therapy. Herein, we pro...
Tallennettuna:
| Julkaisussa: | ACS Med Chem Lett |
|---|---|
| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Chemical
Society
2018
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6231183/ https://ncbi.nlm.nih.gov/pubmed/30429951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00199 |
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