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Mechanism of action of the viral chemokine-binding protein E163 from ectromelia virus
Chemokines interact with glycosaminoglycans (GAGs) at the cellular surface and to specific cell-surface receptors to activate signaling pathways. The GAG interaction allows the formation of a chemotactic gradient of chemokine required for cell haptotaxis and chemokine oligomerization. Poxviruses enc...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6231125/ https://ncbi.nlm.nih.gov/pubmed/30257868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004432 |
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