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Clinical pharmacology of alemtuzumab, an anti‐CD52 immunomodulator, in multiple sclerosis

Alemtuzumab, a humanized anti‐CD52 monoclonal antibody, is approved for treatment of relapsing multiple sclerosis (MS). In the Phase II/III trials, patients received 12 or 24 mg/day of alemtuzumab in two treatment courses (5 days for course 1 and 3 days for course 2), 12 months apart. Serum concentr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Exp Immunol
Main Authors: Li, Z., Richards, S., Surks, H. K., Jacobs, A., Panzara, M. A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231011/
https://ncbi.nlm.nih.gov/pubmed/30144037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13208
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