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Low plasma stem cell factor combined with high transforming growth factor-α identifies high-risk patients in pulmonary arterial hypertension

In pulmonary arterial hypertension (PAH), severe vasoconstriction and remodelling of small pulmonary arteries result in high mortality. Receptor tyrosine kinases and their ligands, such as transforming growth factor (TGF)-α, modulate proliferation in PAH. Although the receptor tyrosine kinase c-Kit...

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Detalhes bibliográficos
Publicado no:ERJ Open Res
Main Authors: Bouzina, Habib, Rådegran, Göran
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230818/
https://ncbi.nlm.nih.gov/pubmed/30443557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00035-2018
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