Different effects of global osteopontin and macrophage osteopontin in glomerular injury

Osteopontin (OPN) is a pro-and anti-inflammatory molecule that simultaneously attenuates oxidative stress. Both inflammation and oxidative stress play a role in the pathogenesis of glomerulonephritis and in the progression of kidney injury. Importantly, OPN is highly induced in nephritic kidneys. To...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Trostel, Jessica, Truong, Luan D., Roncal-Jimenez, Carlos, Miyazaki, Makoto, Miyazaki-Anzai, Shinobu, Kuwabara, Masanari, McMahan, Rachel, Andres-Hernando, Ana, Sato, Yuka, Jensen, Thomas, Lanaspa, Miguel A., Johnson, Richard J., Garcia, Gabriela E.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230752/
https://ncbi.nlm.nih.gov/pubmed/29717936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00458.2017
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