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Effect of Tim23 knockdown in vivo on mitochondrial protein import and retrograde signaling to the UPR(mt) in muscle
The mitochondrial unfolded protein response (UPR(mt)) is a protein quality control mechanism that strives to achieve proteostasis in the face of misfolded proteins. Because of the reliance of mitochondria on both the nuclear and mitochondrial genomes, a perturbation of the coordination of these geno...
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| Published in: | Am J Physiol Cell Physiol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6230686/ https://ncbi.nlm.nih.gov/pubmed/29949403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00275.2017 |
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