Fibrosis Development in HOCl-Induced Systemic Sclerosis: A Multistage Process Hampered by Mesenchymal Stem Cells

Objectives: Skin fibrosis is the hallmark of systemic sclerosis (SSc) a rare intractable disease with unmet medical need. We previously reported the anti-fibrotic potential of mesenchymal stem cells (MSCs) in a murine model of SSc. This model, based on daily intra-dermal injections of hypochlorite (...

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Udgivet i:Front Immunol
Main Authors: Maria, Alexandre T. J., Toupet, Karine, Maumus, Marie, Rozier, Pauline, Vozenin, Marie-Catherine, Le Quellec, Alain, Jorgensen, Christian, Noël, Danièle, Guilpain, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230680/
https://ncbi.nlm.nih.gov/pubmed/30455706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02571
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